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Gastroenterology and Hepatology

Gastroent Hepatol 2021; 75(5): 390–398. doi: 10.48095/ccgh2021390.

Pancreatic cancer screening: ready for prime time?

Petr Vaněk1, Peter Slodička1, Tomáš Tichý1, Jana Tesaříková2, Hana Švébišová3, Radim Kovář4, Daniela Kurfürstová5, Mária Janíková6, Veroniko Woitková6, Martin Procházka6, Přemysl Falt  1,7, Vincent Zoundjiekpon  1, Ondřej Urban1

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Early detection of pancreatic cancer is considered to be the most effective way to improve survival. Individuals with familial occurrence or genetic susceptibility syndromes have an increased risk of developing pancreatic cancer. Current guidelines are based on evidence of the benefits of systematic surveillance in high-risk individuals and emphasize the potential of screening programs to affect overall survival. This type of screening has not yet been introduced in the Czech Republic even though such programs are already being established in other countries. With this review we aim to summarize knowledge about hereditary and familial pancreatic cancer and issue a call for collaboration on a pilot screening program.


pancreatic carcinoma, hereditární karcinom pankreatu, onkologický screening

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