Non-steroidal anti-inflammatory drugs induced colopathy, mimicking Crohn's disease
Laura Gombošová Orcid.org 1, Mária Zakuciová Orcid.org 2, Eduard Veseliny Orcid.org 3, Ivica Drahovská Orcid.org , Marián Švajdler Jr. Orcid.org 4, Juraj Bober Orcid.org , Mária Oetterová Orcid.org
+ Affiliation
Summary
The authors describe the case of a 47-year-old woman with rheumatoid arthritis who took, in the long term, nonsteroidal anti-inflammatory drugs (NSAID). Her state was complicated by sideropenic anaemia with high inflammatory humoral response during complete rheumatological therapy. She was examined by a gastroenterologist. Colonoscopy revealed severe colitis, which was preliminarily evaluated as a Crohn's disease and a complete therapy including infliximab was administered. However, her condition did not improve and repeated colonoscopy was carried out. This investigation revealed a worse finding with severe continuous ulcerationsof the large bowel. The diagnosis was re-evaluated for NSAID induced colopathy. The previous therapy was stopped and colectomy with ileosigmoideostomy was performed. After surgery the patient was feeling well, had no anaemia, and the humoral anti-inflammatory response decreased. The authors present a review of NSAID induced colopathy which can mimic Crohn's disease.
Keywords
Crohn’s diseaseTo read this article in full, please register for free on this website.
Benefits for subscribers
Benefits for logged users